Two-stage strategies to detect gene × gene interactions in case-control data
نویسندگان
چکیده
منابع مشابه
Two-stage strategies to detect gene × gene interactions in case-control data
Large genetic association studies based on hundreds of thousands of single-nucleotide polymorphisms (SNPs) are a popular option for the study of complex diseases. The evaluation of gene x gene interactions in such studies is a sensible method of capturing important genetic effects. The number of tests required to consider all pairs of SNPs, however, can lead to a computational burden, and effic...
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ژورنال
عنوان ژورنال: BMC Proceedings
سال: 2007
ISSN: 1753-6561
DOI: 10.1186/1753-6561-1-s1-s135